Small-molecule Drug Drives Cancer Cells to Suicide

To contact us Click HERE



This is a breakthrough using a failed protocol and a possible gamechanger for brain tumors in particular.
I wonder how it may work with a baking soda protocol happening aswell to block the ability of the cancer to respond to a direct attacklike this. These are simple ideas but we surely need the data and itis safe enough to push that envelop.
We continue to see a wide range of new therapeutic approaches comingon board and what is becoming badly needed is way more directinvolvement with patients and their doctors to produce a far largerempirical database to support this work.


Small-molecule drugdrives cancer cells to suicide
Studies in mice showtherapy is effective even in hard-to-treat brain tumours.
Zoe Cormier
07 February 2013
http://www.nature.com/news/small-molecule-drug-drives-cancer-cells-to-suicide-1.12385
Cancer researchershave pinned down a molecule that can kick-start the body’s owntumour-destroying systems, triggering cell death in cancerous but nothealthy tissue in mice.
The molecule, TIC10,activates the gene for a protein called TRAIL(tumour-necrosis-factor-related apoptosis-inducing ligand), which haslong been a target for cancer researchers looking for drugs thatwould avoid the debilitating effects of conventional therapies.
“TRAILis a part of our immune system: all of us with functional immunesystems use this molecule to keep tumours from forming or spreading,so boosting this will not be as toxic as chemotherapy,” says WafikEl-Deiry, an oncologist at Pennsylvania State University in Hersheyand lead author of the study, which is published today in ScienceTranslational Medicine1.
Experimentsshowed that TIC10 had potent effects against a variety oftumours, including breast, lymphatic, colon and lung cancer. It wasespecially effective at triggering cell suicide in glioblastoma, akind of brain tumour that is notoriously difficult to treat2. Micewith glioblastomas that were treated with TIC10 in combination withbevacizumab — a drug used against diseases including brain tumours,and sold under the name Avastin — survived three times as long asuntreated mice. Even mice treated with TIC-10 alone still had bettersurvival rates (6% longer) than those treated with bevacizumab alone.
Quick andcollaborative
El-Deiry says thatTIC10 is so effective because it is much smaller than proteins thathave previously been tested as TRAIL-based drugs. The molecule is socompact that it can cross the blood–brain barrier, which separatesthe main circulatory system from the brain. This barrier normallyacts to prevent hazardous agents such as microbes from infecting thebrain, but can also thwart anti-cancer drugs by keeping them out. “Wedidn’t actually anticipate that this molecule would be able totreat brain tumours — that was a pleasant surprise,” saysEl-Deiry.
Furthermore, it seemsthat TIC10 activates the TRAIL gene not only in cancerous cells, butalso in healthy ones. This gives it enormous potential to create a'bystander effect', in which apoptosis — or cell death — isinduced in cancer cells immediately next to healthy ones. Healthycells are also stimulated to increase the amount of TRAIL receptorson their cell surface. These receptors can then bind to the adjacentcancerous cells, triggering their demise. “It’s almost likeTRAIL-plus — it does so much more,” says El-Deiry.
Tough TRAIL
This is by no meansthe only mechanism thought to trigger cell death in cancer. Inparticular, cancer researchers have been developing a number ofdrugs, including TRAIL-based therapeutics, that work by activatingthe cellular messenger tumour protein 53 (p53). But p53-based methodsare not always effective, says El-Deiry. "Most tumours havedysfunctional p53, so in order to develop new therapeutics forcancer, one needs them to be effective in tumours with mutated p53,”he explains. His team's approach bypasses p53 entirely.
Although the study waslimited to mice, the team is confident that a similar approach wouldwork in humans. Other researchers are sceptical, in part becauseTRAIL-based strategies have not lived up to past hype.
The potential for TRAIL to usher in a new age in cancer therapywas first identified in the mid-1990s3. However, although earlyclinical trials for TRAIL-based therapies showed little toxicity,they were not very successful at treating cancer, says AndrewThorburn, an oncologist at the University of Colorado Denver, whoco-authored a review on the subject last year4. “All the largeclinical trials found no significant survival benefit to addingTRAIL-based therapeutics to standard treatments,” he ads. Manylarge biomedical research groups have shelved their TRAIL-baseddrugs.

new Bone Repair Therapies on Nanoscale Surfaces

To contact us Click HERE



 Step by step we are getting there. This approach opens the door toartificially mold absent bone and then use it as a scaffold toreplace that bone. It will no longer be necessary to build out thewhole organ or bone. We are entering the age of full scale tissueengineering and ultimately complete restoration of a human body.
At this point I see little to thwart us. What is in front of us aresolvable problems and what is behind us are formally dauntingunsolvable problems. What I find gratifying is that no one dares saynever anymore.
Even my dentist has got into the spirit of the times and I learnedrecently from him that an actual nerve is not necessary at all interms reconstructing the mouth. Here we have the technology forrebuilding a weakened jaw and adding an actual tooth bud cannot befar behind. That bit about the nerve is worth remembering as ournervous system manages the full build out of a human being. Nothaving to hook up a lot of mature nerves is a bonus. In the meantimeit is also taking little to now stimulate regrowth anyway.
As posted before, this is the penultimate decade for medical mastery. All the big problems are advancing to solution side by side.
Stem cellbreakthrough could lead to new bone repair therapies on nanoscalesurfaces
Ref: 13/2711 February 2013
http://www.southampton.ac.uk/mediacentre/news/2013/feb/13_27.shtml

Scientists at theUniversity of Southampton have created a new method to generate bonecells which could lead to revolutionary bone repair therapies forpeople with bone fractures or those who need hip replacement surgerydue to osteoporosis and osteoarthritis.

The research,carried out by Dr Emmajayne Kingham at the University of Southamptonin collaboration with the University of Glasgow and published in thejournal Small, cultured human embryonic stem cells on to the surfaceof plastic materials and assessed their ability to change.

Scientistswere able to use the nanotopographical patterns on the biomedicalplastic to manipulate human embryonic stem cells towards bone cells.This was done without any chemical enhancement. 

The materials,including the biomedical implantable material polycarbonate plastic,which is a versatile plastic used in things from bullet proof windowsto CDs, offer an accessible and cheaper way of culturing humanembryonic stem cells and presents new opportunities for futuremedical research in this area.

ProfessorRichard Oreffo, who led the University of Southampton team, explains:“To generate bone cells for regenerative medicine and furthermedical research remains a significant challenge. However we havefound that by harnessing surface technologies that allow thegeneration and ultimately scale up of human embryonic stem cells toskeletal cells, we can aid the tissue engineering process. Thisis very exciting.

“Ourresearch may offer a whole new approach to skeletal regenerativemedicine. The use of nanotopographical patterns could enable new cellculture designs, new device designs, and could herald the developmentof new bone repair therapies as well as further human stem cellresearch,” Professor Oreffo adds.

The study wasfunded by the Biotechnology and Biological Sciences Research Council(BBSRC).

This latestdiscovery expands on the close collaborative work previouslyundertaken by the University of Southampton and the University ofGlasgow. In 2011 the team successfully used plastic withembossed nanopatterns to grow and spread adult stem cells whilekeeping their stem cell characteristics; a process which is cheaperand easier to manufacture than previous ways of working.

Dr NikolajGadegaard, Institute of Molecular, Cell and Systems Biology at theUniversity of Glasgow, says: "Our previous collaborativeresearch showed exciting new ways to control mesenchymal stem cell –stem cells from the bone marrow of adults – growth anddifferentiation on nanoscale patterns. 

“This newSouthampton-led discovery shows a totally different stem cell source,embryonic, also respond in a similar manner and this really starts toopen this new field of discovery up. With more research impetus, itgives us the hope that we can go on to target a wider variety ofdegenerative conditions than we originally aspired to. This result isof fundamental significance." 

Vietnam Lizard Being Encounter

To contact us Click HERE




I have posted several reports now aboutthese lizard beings. They are all rather substantial in terms ofdetail and relay a tale of an evolved Terran race established onEarth for millions of years. This is a creditable proposition aseven the fossil record supports that possibility. Almost allencounters appear either underground or close to such access.
It is relayed to us that thesecreatures reside deep underground in large formed habitats with ampleaccess to the surface for rare intrusions. Again we are entering afuture in which our mastery of material strength will allow superiorunderground construction. We do fine at present, but it is clearalso that a lot better is plausible and desirable.
What we do get is rare close encountersand they will chase us off. In this case, they were surprised by thefire power and simply bugged out. That was the only rational thingto do.
Very important here is the descriptionof the cave itself. The sides are smooth, with precise grooving andare tapered toward the top to distribute pressure. It is clearly acorrect design model that we do not use at all because we still relyon blasting. This is completely new information.
Most certainly this entry was thenopen. The grooves would likely carry a blocking plug that was thenretracted. This is again advanced methodology meant to preventunnecessary discovery.
As an aside, way more data has been shared in a couple of separate reports than we have for any other oddity.  Most important though is that they claim to be non alien and as mankind could also move underground if it proved desirous as our culture advances, none of this is unreasonable.  My difficulty is that we have on hand several deeply detailed reports regarding several plausible scenarios that are best described as unique, unconfirmable (This one by way is confirmable and likely has been ) and way too good to be true.  They all could easily have been lifted out of 1930's pulp fiction.
In short, they are stories that are too well written and that i could have made up out of whole cloth myself.  you get the point.
LizardBeings: Encounter & Engagement
TUESDAY, FEBRUARY 12, 2013
http://naturalplane.blogspot.ca/2013/02/lizard-beings-encounter-engagement.html
During the past months I have collected anecdotes from readerswho had personal experiences or were told of cryptids / anomalousencounters in Vietnam and other parts of Indochina. I received aparticular narrative that was much different than the others that hadbeen forwarded to me...so I decided to publish it separately. Thepost is a compilation of 3 emails, which included answers to a few ofmy questions. The man who provided this information was, at the timeof the incident, a U.S. Army corporal...who has since retired fromthe military after a lengthy career. He did not give me specifics asto his unit and mission...but feels strongly that his experienceshould be told. He provided two identification references, whichchecked out. Overall, this man served a distinguished military careerand his reputation is quite admirable from what I have seen. Some ofthe information has been edited at the request of the witness: [Lon]
In 1970 I was servingas a corporal in the U.S. Army – deployed to South Vietnam in anregion about 30 miles south of the DMZ. At the time I wassecond-in-command of a squad of soldiers. We had setup a bivouac in ajungle area that had a few steep hills. That evening my section wasordered to patrol one of the small valleys west of the encampment. Wemoved out led by our sergeant.

Not long afterentering one of the small valleys we detected movement ahead of us.It seemed to be scattered activity, so we doubted it was VC but weweren’t positive. We hunkered down for about 15 minutes gettingoccasional glimpses of something moving within the trees and brush.There wasn’t enough light to detect what we were observing eventhough the moonlight was bright that night.

After awhilethe activity halted, so we continued to move slowly through thevalley. As we approached a sheer wall on the hill it looked likesomeone or something had stacked large stones and boulders in thepass in front of us. There was also an opening in the hill sidethat looked like a cave entrance – approximately 5 foot highand 3 foot wide narrowing at the top. When observing thepassageway, it appeared to have been cut away by machinery – theedges were smooth with small even-spaced grooves.

We werepuzzled by this because we had never seen enemy caves like this –just underground tunnels. The sergeant suggested that it may be a VCsupply depot, so we started to assess how we were going toinvestigate the cave.

About thistime, things got very strange.

Webegan to notice a putrid odor emanating from the cave entrance –the only thing I can compare it to was rotting eggs and human decay.It was so revolting that a few of the soldiers were becoming ill andstarted to back away into the jungle – including the sergeant. Iwas directing a light into the entrance in order to observe anything,but there was a haze that was impossible to see through. We had noidea what was before us.

Theentire squad took a position in the heavy brush approximately 150feet from the entrance – far enough not to be detected but closeenough to observe the cave entrance. We quietly remained there forwhat seemed like forever. The jungle was strangely calm though weheard rumbling sounds coming from the distance. It was really eerie.The sergeant was sitting near me talking to himself - it was obviousthat he was frightened. I was looking at the rest of the squad –each had wide eyes and scanning the area. No one was going to dozeoff during this patrol.

After severalhours, dawn was approaching and it started to lighten up. I checkedmy watch – it was just before 0500 hours. Just then we noticedmovement in front of the cave. A being (I first thought it was a man)moved through the entrance into the clearing in front of the cave. Asit stood up from a crouch it stood at least 7 foot high and startedto look in our direction. At that time, another similar-lookingcreature was moving out of the cave. They were making hellish‘hissing’ sounds and looking directly at us.

The only way Ican describe these beings is that they looked like upright lizards.The scaly, shiny skin was very dark – almost black. Snake-likefaces with forward set eyes that were very large. They had arms andlegs like a human but with scaly skin. I didn’t notice a tail –though they wore long one-piece dark green robes along with a darkcap-like covering on their heads. I never noticed if they hadanything on their feet.

No one gavethe order – it seemed like the entire squad opened fire at once.Every piece of vegetation between us and them was quickly shearedaway. I yelled out a cease-fire order – at the same time I waslooking in the direction of the cave. There was nothing there. Weimmediately checked our flank in case these things circled around us– but there was nothing.

Aswe approached the cave, ready to resume action if needed, it becameapparent that the beings had escaped – most likely back into thecave. It was soon decided to set charges and close the cave entrance.

When wereturned to camp we all seemed to be in a daze. There was littlediscussion of the incident and we were never debriefed – so I knowthe sergeant never filed a report. Then again, if he did, it was keptquiet by the brass.

NOTE: Well...Itold you. None of the anecdotes or narratives I received match thisone. But then again, I never know what will turn up in my mailbox. Ilook forward to receiving your well-written sighting and incidentreports. Thanks...Lon

Giant Sloths of the Applachians

To contact us Click HERE



Thisis all part of the Appalachians of course andwe actually have a number of plausible cryptids reported over the years.  Bigfoot is of course the most common  but we also have the Giant Sloth and a small hominid that is likely part of the Lucy lineage. These are the best suspects.  It Ihave taken a lesson from uncovering the Giant Sloth is that it is way too easyto misidentify such a creature in a glimpse. However if it is in the fossil record, do not discount its presence inthe modern era even if confined to a small range.
Here we have an excellent report of what I am suspect is the Giant Sloth.  The second report is likely something we knowand you have my guess of a tom cat.  Thisis also not the first time that horns have been associated with the Giant Sloth.  Otherwise the highly robust claws wereobserved and the visible fangs.  Generally i am seeing the huge claws reported as confirmation and without them we do not have a Giant Sloth.
Confrontingfarmers tells me that it may have established its range locally and was takingadvantage of the bounty.  Then itpossibly backed off or may simply know enough to avoid guns.  After this story got around it is a suretythat everyone began to pack.  It is evenpossible that it was simply passing through to a remote range and we got thereports of its foraging.
It is most likely that this confirms that males do grow goat like horns although their size is not described.  It alsoshows us that the creature can be opportunistic and must never be trusted.  It may also be more of a daytime hunter thanexpected.

For the moment, i am likely the only person out there looking for the Giant Sloth as a small subset of all reports.  We alraedy have enough good quality reports to confirm that the creature is out there.
Lancaster County, Pennsylvania - August1973 – various
http://naturalplane.blogspot.ca/2013/02/odd-sighting-in-york-county-pa.html
An ungodly looking creature created havoc amongthe local god-fearing Amish community. Witnesses described the creature asfollowing: The size of a good heifer, gray in color with a white mane. It hadtiger like fangs and curved horns like a Billy goat. It ran upright on longlegs, and had long grizzly claws. In one incident, the creature sent a team of horses and two brothers flying when it approached their hay wagon. The following day, a man was cutting weeds on his farm about five miles from the previous incident when he heard a fierce roar and turned to see a monster with three horns and a tail charging in his direction. He raised his scythe to defend himself, only to have the implement ripped from his hands. At that point, the man wisely decided to turn both cheeks to the monster and escaped as fast as he could run. A day later a woman was feeding poultry on a farm midway between the two earlier incidents when she heard a commotion and turned to see the creature in the act of snatching a goose in each of its hands. She bravely ran toward the thing, waving her apron. The woman managed to recover one of her geese when the creature threw it at her, knocking her to the ground in the process. The interloper then escaped with the remaining bird in hand.

Source: Phillip LRife, America'sNightmare Monsters
I found aninteresting account posted on Stephen Wagner's Paranormal About by Stacy L. Theincident took place recently in York, Pennsylvania...a location I amvery familiar with. I have received several odd cryptid sightings from in andaround York and Lancaster counties (which are in south-central Pennsylvania...where I grew up and just north of myresidence in Baltimore, MD). Was this a natural sighting...or a lostpet?


I wasjust relaxing in my house and watching some TV. We have double sliding doorswith windows facing our backyard, and I can see outside from where I waslounging on the couch.

That's when something began moving in the corner of my vision. When I glancedover, I noticed our 10-foot-high dogwood tree on the very end bordering ouryard from the neighbors was shaking violently. I couldn't figure out what kindof animal, aside from a human, could shake an entire tree like that. I stood upand walked over to the window to peer out.

There are also several extremely large pine trees bordering along the end ofthe backyard and I couldn't see anything through the thick foliage, even thoughthe sun was shining brightly in the sky. The dogwood continued to shake, andthen to my astonishment an enormous gray creature jumped from one of thedogwood's flimsy branches and into a huge pine nearby.

I only glimpsed it for about three seconds at most, but I definitely got a goodlook at it, and it was like nothing I have ever seen before. The creature wasrather large, perhaps around 4 feet in length and about the size of a fox. Itwas all gray except for its long skinny tail that had black and white stripesalong it, like those lemurs from Madagascar. Its front end wassomewhat slouched down, as if it had short front legs and large powerful backlegs, like how a kangaroo would look.

It was the weirdest creature I had ever seen. Unfortunately, I didn't get a look at its head as it quickly vanished into the pine. A few minutes later, I was outside rooting through the leaves and long grass at the end of the yard looking for footprints and maybe to catch a sighting of the creature, but I didn't find anything. Yet I know what I saw.
[ a ten foot dog wood is not a lot of tree somovement is very likely.  The stripes onthe tail suggest that we are dealing with a big old tom cat who for some reasonwas getting away from something.  Arclein ]

I live in York, Pennsylvania, and such creatures like thatdon't live in this area. If I absolutely had to call it a specific animal, Iwould say it was a lemur, but the tail wasn't bushy, but very slender and agilelike a cat's. Wish I had taken a picture.

I haven't seen it since that day, but there have been weird scratching noisesbelow my bedroom window at night ever since I saw the creature and I wonder ifthe two are related or if its another incident that coincidentally justhappened in the same time period. And I wonder if I should report the sighting.If I should, who do I report to?
So...I previously mentioned that I had receivedodd reports from York and Lancaster counties over the years.

Aging Boomer's Blog

To contact us Click HERE
Hey, a short entry today to plug my relatively new website where I'm blogging on a regular basis about getting older and all the trappings that come with it.

I named the site cleverly...

AgingBoomersBlog.com

Okay, so that's not so clever. But it was an available domain name that more-or-less reflected what it was going to be about.

Anyway, if you're an aging boomer, surf on over and bookmark my new site. Then spend some time there reading the many posts already up and then spending some more time commenting and moving the discussions forward.

I promise my AgingBoomersBlog.com will never be dull or boring or politically correct!

Chet "Aging Boomer" Day
Editor, The Natural Health Circus
http://chetday.com/blog

Green 'Space' Slime Baffles Nature Experts

To contact us Click HERE



Here we go again. My conjectureregarding a stratospheric slime mold balloon as unreal as it seemscontinues to bear fruit. Such a balloon would contain methane andrise at night from our swamps into the stratosphere. Very likelythey naturally refract the sun's light to produce high altitudelights which I have seen and has also been called Brown lights aroundmountains were the rising uplifts would jostle them around a lot.
When a meteor strikes, a sharp shockwave is produced and this likely disrupts a large number of suchcreatures that then fall to earth to appear as blobs of slime. Wehave seen that phenomena world wide and often associated with arecent meteor event.
Up there we would never even see thesecreatures unless we had special viewing hardware. To do so we needobservation balloons able to reach the stratosphere and some speciallighting to create contrast. That should work.
Alternatively, we need to captureimages of these forming up and rising out of swamps and that may bemuch easier although I suspect foam making conditions must existwhich we still do not understand. I do not expect to be lucky onthis hunt. However lighting should not affect such a search.
Setting up on the banks of the ponds discussed here would be ideal.


Green 'Space' SlimeBaffles Nature Experts
An unexplainedjelly-like substance which is said to occur during meteor showers hasbeen found on a wildlife park in Somerset.
18 February 2013
http://news.sky.com/story/1053694/green-space-slime-baffles-nature-experts


A "weird"green slime said in folklore to appear at the same time as meteorshit Earth has been found in a birdlife park in Somerset.
The RSPB has appealedfor help in identifying the slime, which is said to be scattered ongrass banks close to pools and lakes around Ham Wall Nature Reservenear Glastonbury.
The jelly-likesubstance could be bacteria, fungus or toad innards, wildlife expertssaid.
Some believe it couldbe a substance that has been written about for centuries called staror astral jelly, which is said to appear in the wake of meteorshowers.
Its appearance hascoincided with a meteor strike in Russia and the harmless fly-by ofan asteroid at a record distance from Earth last week.
Steve Hughes, the RSPBsite manager at Ham Wall, said: "This past week we've beenfinding piles of this translucent jelly dotted around the reserve.
"(It is) alwayson grass banks away from the water's edge. They are usually about10cm (4in) in diameter.
"We've askedexperts what it might be, but as yet no one is really sure. Whateverit is, it's very weird."
Tony Whitehead, anRSPB spokesman for the South West, added: "Although we don'tknow what it actually is, similar substances have been describedpreviously.
"In recordsdating back to the 14th Century it's known variously as star jelly,astral jelly or astromyxin."In folklore itis said to be deposited in the wake of meteor showers."
One of the morefavoured explanations is that it is a form of cyanobacteria calledNostoc.
Others suggest that itis the remains of the regurgitated innards of amphibians such asfrogs and toads, and of their spawn.
Alternatively, it maybe related to the intriguingly named crystal brain fungus.
Mr Whitehead added:"We've read a few articles now, and much speculation.
"One suggested itwas neither animal nor plant, and another that it didn't contain DNA,although it does give the appearance of something 'living'.
"Our reserve teamwill be looking out for the slime over the next few days, but ifanyone can offer any explanations we'd be glad to hear."
The public are beingwarned not to touch the mystery substance, and to inform naturereserve staff if they spot any.

Primal Evil's Physical Basis

To contact us Click HERE




There are two types of evil.  The type this addresses is the worst kind and we will simply label it primal evil and it is strongly associated with a physical flaw in the brain itself.  Evidence exists suggesting that Hitler suffered a war injury to the head and that effected his subsequent behavior.  Other specific cases also typically are associated with brain flaw and this work polices the obvious science.
The other type of evil is derivative evil and it is learned and impressed through the social environment.  This is both forgivable and also modifiable if not outright curable.  That is not necessarily easy as the victim has a whole sense of self bound up in abhorrent behavior.  Recall that it requires time and effort to bring a soldier back down into civilized behavior at best.
My own observations and readinghad come to the general conclusion that primal evil was expressing a physicalabnormality.  This indicates that we havefound at least one such source.  It mayeven be sufficient.  Obviously the nextstep is to diagnose this whenever indicated and if this work is an indication,operate to remove the problem which may be as simple as scaring.  An unlucky blow to the head can inducebleeding and derivative tissue damage and physical scaring.  The same holds true for difficult births.
We now know these people can beidentified and are themselves victims in need of corrective surgery to makethem safe to society.
We should be so lucky as to have an equally simple solution for obsessive learned bad behavior.  Pedophiles, kleptomaniacs and many other obsessives want to be cured.  So far our only avenue open appears to be shamanism and their curious drug therapy.


What evil lurks in the brain? German neurologist says he's found a'dark patch'
By JeremyA. Kaplan
Published February 07, 2013

Read more: http://www.foxnews.com/science/2013/02/07/is-there-dark-evil-spot-in-brain/#ixzz2KS7MGgbM
After studying the brains of violent killers, rapists and robbers,German neurologist Gerhard Roth claims to have found a “dark patch” in thecenter of the brain -- he calls it the evil spot, a genetic source of violentbehavior.
Roth, a professor at the University of Bremen, told Germany news site Bild.de that hehad shown short films to criminals and measured their brain activity. A smallsection at the front of their brains showed no reaction to violent scenes; itremained "dark" when shown dark scenes.
"Whenever there were brutal and squalid scenes, the subjectsshowed no emotions. In the areas of the brain where we create compassion andsorrow, nothing happened,” Roth said.
BioEdge, a blog dedicated to bioethics news, translated Roth's Germaninto English: “This is definitely the region of the brain where evil is formedand where it lurks.”
Not so fast. Human behavior, affect and emotion is likely a far more intricate thing, explained Dr. Steven Galetta, chairman of the neurology department at the NYUSchool of Medicine.
'It’s probably not as simple as X marks the spot for a particularbehavior.'- Dr. Steven Galetta, chairman of the neurology department at the NYU Schoolof Medicine
“People look at the blood flow to one area and they say, ‘aha, this is the evil patch.’ It’s probably a lot more complex than that,” Galetta told FoxNews.com.
“Certain areas are likely important for certain behaviors, certainattitudes. But it’s probably not as simple as X marks the spot for a particularbehavior.”
Roth’s study, according to Bild.de, was conducted for the Germangovernment on violent convicted offenders. He said the dark mass that he hasidentified appears in all CT scans of people with such records -- and takingit out ended their “evil” behavior.Roth did not respond to FoxNews.com requests for more details on hisstudy.
Terre Constantine, executive director of the Brain Research Foundation  andthe former director of the Jack Miller Center for Peripheral Neuropathy,expressed skepticism at the report, but agreed that brain abnormalities such astumors can affect behavior.
“It absolutely can affect the brain and your personality and how youcommunicate. And it can make you aggressive -- not all tumors, of course: itdepends where it is,” Constantinetold FoxNews.com.
Her foundation, which funds research into neuroscience seeking tounderstand the brain’s workings, has aided research similar to Roth's with moreadvanced imaging techniques.
One recent study from a University of Chicago researcher studied parenting behavior. It found activity in the amygdala -- a portion of the brain connected to the limbic system -- correlated to parenting style. It “lit up” in the brains of normal mothers, while “harsh parents” didn’t react to scenes of bad parenting.
“There’s clearly differences in the brain depending on what sort ofdisease or abnormality a person has,” she told FoxNews.com. And many things cancause abnormal behaviors. “They’re either wired differently or there might besome disease that’s causing the brain to atrophy.”
But Constantine agreed with Galetta: Complex topics and behaviors are likely linked to other areas of the brain, rather than concentrated in one “evil area.”
“I would argue it’s probably not the only “evil” spot,” she said.“There are other areas in the brain, there are lots of … empathy areas orviolent areas or just social reaction areas within the brain.”
“This may be one of the spots, but I’d be surprised if it’s the spot.”